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Digoxin 0.5 MG Injection

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsDigoxin
CURRENTLY UNAVAILABLE

Description

Digoxin 0.5 MG Injection is a cardiac glycoside that is used to treat heart failure and atrial fibrillation (a rhythm disorder of the heart). It should be started at lower doses and increased gradually. Close monitoring of blood pressure and heart rate is necessary while receiving this medicine.
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Substitutes

List of substitutes for Digoxin 0.5 MG Injection

Side effects

Major & minor side effects for Digoxin 0.5 MG Injection

Dizziness

Irregular heartbeat

Stomach pain

Pain at the injection site

Anxiety

Confusion

Depression

Skin rash

Diarrhea

Blurred vision

Loss of appetite

Breast enlargement in men

Uses of Digoxin 0.5 MG Injection

What is it prescribed for?

Congestive Heart Failure

This medicine is used for the treatment of congestive heart failure, which is a type of heart disease, characterized by thickening of the walls of the left ventricle and reduced blood circulation to the body.

Atrial Fibrillation

This medicine is used for the treatment of atrial fibrillation which is a type of heart disease characterized by irregular heartbeats and leads to decreased blood flow.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of this medicine can be observed in 5 to 30 minutes after the administration of the dose.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to digoxin or any other inactive ingredients present along with the formulation.

Ventricular fibrillation

This medicine is not recommended for use in patients with ventricular fibrillation (rhythm disorders of the ventricles; the lower chambers of the heart).

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

Sinus Bradycardia and Sino-atrial Block

This medicine should be used with caution in patients suffering from heart disorders due to the risk of low blood pressure and heart block. Close monitoring of heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Digoxin toxicity

This medicine has an increase in the risk of toxicity due to its narrow therapeutic index. Close monitoring of blood levels is necessary. Any symptoms of anorexia, nausea, vomiting, visual changes and cardiac arrhythmias should be informed to the doctor.

Hypokalemia and Hypomagnesemia

This medicine when used with potassium-depleting diuretics, may increase the risk of low potassium (Hypokalemia) and low magnesium (Hypomagnesemia) blood levels. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in elderly population

This medicine should be used with extreme caution in elderly patients above 65 years of age due to the risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving and operating machinery

This medicine may cause symptoms such as dizziness, visual disturbances, fainting, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Clarithromycin

Pantoprazole

Captopril

Atorvastatin

Calcium gluconate

Atenolol

Itraconazole

Amiodarone

Quinidine

Disease interactions

Hypercalcemia

This medicine should be used with extreme caution in patients with hypercalcemia (high blood calcium levels) due to the increased risk of severe adverse effects. The blood calcium levels should be corrected prior to initiating treatment with this medicine. Regular monitoring of blood calcium levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypocalcemia

This medicine should be used with extreme caution in patients with hypocalcemia (low blood calcium levels) due to the increased risk of severe adverse effects. The blood calcium levels should be corrected prior to initiating treatment with this medicine. Regular monitoring of blood calcium levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Thyroid Dysfunction

This medicine should be used with caution in patients with thyroid dysfunction due to the increased risk of worsening of the patient's condition. Close monitoring of thyroid function is necessary while receiving this medicine. Any symptoms of irritability, irregular heartbeats, nervousness, and weight loss should be reported to the doctor. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Acute myocardial infarction

This medicine should be used with caution in patients suffering from acute myocardial infarction due to the increased risk of severe adverse effects. Close monitoring of heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

This medicine works by decreasing the workload to the heart by controlling the heart rate with its action on ion channels.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Group V antiarrhythmics, Cardiac Glycosides, Inotropic agents

Schedule

Schedule H

[Internet]. 2020 [cited 18 March 2020]. Available from:

https://www.medicines.org.uk/emc/product/5290/smpc

Digoxin - DrugBank [Internet]. Drugbank.ca. 2020 [cited 15 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB00390

DailyMed - Digoxin injection [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 18 March 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=017021a4-25a4-4914-aab3-c21daf97ea50

Related Questions

Question:
What happens if we take 30 tablets of digoxin mixed in a solution and taken orally.
Answer from Dr. Narendra Kumar Jha
No medicine is child's play and should not be used until prescribed by a physici...more
Question:
She used to take digoxin 0.25 mg for persistent atrial fibrillation. Doctor suddenly reduced the dos...more
Answer from Dr. Sharath Kumar K N
Hello, I went through your query, this dioxin has very narrow therapeutic index ...more
Question:
My Dad is having difficulty breathing as a result of heart failure and 250mcg of digoxin as prescrib...more
Answer from Dr. Vasudeva Chetty Pakala
Hello Mr., your father might be dehydrated due to diuretic tablets given for hea...more
Question:
I Have had svt a couple times and it required going to the hospital to slow it down. They have me on...more
Answer from Dr. Sanjat Chiwane
If you are having frequent SVT, I would recommend that you it ablated. There are...more
Question:
I have a heart problem I took a corlanor around 10am is it ok to take digoxin
Answer from Dr. Anand Chopda
Need to know more about heart problem and then can guide. Kindly chat and consul...more
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Information on this page was last updated on 16 Apr 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.