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Colstim 300 mg Injection

Manufactured byZydus Cadila
ContainsFilgrastim
CURRENTLY UNAVAILABLE

Description

Colstim 300 mg Injection is a human granulocyte colony-stimulating factor (G-CSF) analog. It stimulates the growth of white blood cells and helps in decreasing the chances of infection in patients who are undergoing chemotherapy procedures for cancer. Patients with blood disorders are advised not to use this medicine.
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Substitutes

List of substitutes for Colstim 300 mg Injection

Fastograf 300 mg Injection
Alkem Laboratories Ltd.
Filcad 300 mg Injection
Cadila Pharmaceuticals Ltd.
Imumax 300 mg Injection
Abbott Healthcare Pvt. Ltd.

Side effects

Major & minor side effects for Colstim 300 mg Injection

Stomach pain

Hair loss

Constipation

Nausea or Vomiting

Fever and chills

Bone pain

Loss of appetite

Weight loss

Swelling or inflammation of mouth

Uses of Colstim 300 mg Injection

What is it prescribed for?

Neutropenia caused by chemotherapy

This medicine is used to reduce the incidence of infection in patients receiving myelosuppressive anti-cancer drugs.

Bone Marrow Transplantation

This medicine is used to treat febrile neutropenia, the fever caused due to decreased neutrophil count in patients receiving chemotherapy followed by bone marrow transplantation.

Peripheral Progenitor Cell Transplantation

This medicine is used before the procedure of leukapheresis to mobilize the autologous hematopoietic progenitor cells into the peripheral blood for collection.

Chronic Neutropenia

This medicine is used to reduce the incidence of infection, fever, and oropharyngeal ulcers in patients with chronic neutropenia.

Neutropenia caused by radiation

This medicine is used to increase the survival rate in patients who have received high doses of myelosuppressive radiation.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for this medicine to show its action is not clinically established.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to filgrastim or any other inactive ingredients present in the formulation.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

General warnings

Splenic Rupture

This medicine should be used with caution due to the increased risk of splenic rupture. Patients having abdominal and/or shoulder tip pain while taking this medicine should consult the doctor immediately. Your doctor may advise you to stop the medicine based on your clinical condition.

Acute Respiratory Distress Syndrome (ARDS)

This medicine has been shown to cause Acute respiratory distress syndrome in rare cases. Discuss the risks and benefits with your doctor before taking this medicine. Report any symptoms of fever or respiratory distress to the doctor on priority. Replacement with a suitable alternative might be required based on the clinical condition.

Sickle cell crisis

This medicine not recommended for use in patients with a known history of sickle cell disease due to the increased risk of serious and life threatening reactions. Discuss the risks and benefits with your doctor before taking this medicine. Replacement with a suitable alternative might be required based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Cisplatin

Fluorouracil

Doxorubicin

Bleomycin

Cytarabine

Disease interactions

Glomerulonephritis

This medicine should be used with caution in patients with Renal dysfunction due to the increased risk of glomerulonephritis. Report to the doctor any symptoms such as swelling of ankles and face, blood in the urine, dark colored urine, or decreased urine output immediately. An alternative treatment option should be considered based on the clinical condition of the patient.

Myeloid Tumors

This medicine should be used with caution in patients with Myeloid tumors due to the increased risk of tumor growth. Report to the doctor all your medical conditions before taking this medicine.

Leukocytosis

This medicine should be used with caution in patients with Leukocytosis due to the increased risk of excessive white blood cell count. Appropriate dose adjustments or replacement with an alternative medicine should be done under your doctor's supervision.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

This medicine works by stimulating the production of white blood cells and thus helps to fight against infections.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Colony stimulating factors

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2020 [cited 1 June 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/103353s5183lbl.pdf

Filgrastim Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 1 June 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a692033.html

[Internet]. Medicines.org.uk. 2020 [cited 1 June 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.3000.pdf

DailyMed - NEUPOGEN- filgrastim injection, solution [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 1 June 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97cc73cc-b5b7-458a-a933-77b00523e193

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Information on this page was last updated on 6 Jul 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.