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Description
Codine Sulphate 15 mg Tablet is an opioid pain medication used to relieve mild to moderately severe pain. It is used in patients who have not adequately responded to non-opioid analgesics. It may also be used with other medicines to suppress the cough.
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Substitutes
List of substitutes for Codine Sulphate 15 mg Tablet
Side effects
Major & minor side effects for Codine Sulphate 15 mg Tablet
Constipation
Dizziness and Drowsiness
Increased heartbeat
Confusion
Headache
Loss of appetite
Stomach pain
Difficulty urination
Rash
Nausea and Vomiting
Uses of Codine Sulphate 15 mg Tablet
What is it prescribed for?
Mild to moderately severe pain
This medicine is used to relieve mild to moderately severe pain in patients where treatment with an opioid is appropriate or who have not adequately responded to non-opioid analgesics.
Cough
This medicine may be used with other medicines to reduce coughing.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The effect of this medicine can be observed within 30 to 60 minutes after administration of the dose.How long do the effects of this medicine last?
The effect of this medicine lasts for an average duration of 4 to 6 hours.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.Is this a habit forming medicine?
This medicine may be habit-forming in some cases, especially after prolonged use.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to codeine or any other inactive ingredients present along with the formulation.
Respiratory depression
This medicine is not recommended for use in patients with respiratory depression, in the absence of resuscitative equipment, due to the increased risk of worsening of the patient's condition.
Acute or severe bronchial asthma
This medicine is not recommended for use in patients with acute or severe bronchial asthma, in the absence of resuscitative equipment, due to the increased risk of worsening of the patient's condition.
Post operative pain
This medicine is not recommended for pain relief in children aged below 18 years who have undergone tonsillectomy and/or adenoidectomy.
Monoamine oxidase inhibitors (MAO)
This medicine is not recommended for use in patients receiving Monoamine oxidase inhibitors (MAO) due to the increased risk of serious adverse effects.
Paralytic ileus
This medicine is not recommended for use in patients with gastrointestinal obstruction, including paralytic ileus due to the increased risk of worsening of the patient's condition.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Infectious diarrhea
This medicine should be used with extreme caution in patients with infectious diarrhea since it may worsen the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Acute alcohol intoxication
This medicine is not recommended for use in patients with acute alcohol intoxication exhibiting depressed vital signs due to the increased risk of severe respiratory depression and death. Replacement with a suitable alternative should be considered under your doctor's supervision.
Drug dependence
This medicine has the potential to cause drug dependence and abuse. This risk is especially higher if the medicine is used for a prolonged period of time. Patients should be monitored closely for any change in mood and behavior during treatment with this medicine. Abrupt discontinuation is not recommended since it may cause withdrawal symptoms. Withdrawal of therapy should be done gradually with close monitoring of the patient.
Intracranial pressure
This medicine should be used with caution in patients with head injury or intracranial lesions since it may elevate the intracranial pressure and worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Biliary spasm
This medicine should be used with caution in patients with biliary or gallbladder diseases due to the increased risk of biliary spasm and worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Liver impairment
This medicine should be used with caution in patients with impaired liver function since it may worsen the patient's condition. Close monitoring of liver function, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Kidney impairment
This medicine should be used with caution in patients with impaired kidney function since it may worsen the patient's condition. Close monitoring of kidney function, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Cessation of therapy
Do not abruptly discontinue this medicine in a physically-dependent patient. When the patient no longer requires therapy with this medicine, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for any signs and symptoms of withdrawal. If the patient develops signs or symptoms of withdrawal, raise the dose to the previous level and taper more slowly.
Driving and operating machinery
This medicine may cause difficulty in concentrating, drowsiness, dizziness, confusion, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Use in children
This medicine is not recommended for use in patients less than 12 years of age for pain relief.
It is not recommended for use in patients less than 18 years of age for treating cough.
Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Aripiprazole
Linezolid
Monoamine oxidase inhibitors
Ramelteon
Alvimopan
Disease interactions
Hypotension
This medicine should be used with caution in patients with a known history of hypotension due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Addison's Disease
This medicine should be used with caution in patients with a known history of Addison's disease due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Hypothyroidism
This medicine should be used with caution in patients with hypothyroidism (a condition where the thyroid gland does not make enough hormones) due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Seizure disorders
This medicine should be used with caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Arrhythmias
This medicine should be used with caution in patients with Arrhythmias due to the increased risk of bradycardia (a slow heart rate) and worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Urinary tract obstruction
This medicine should be used with caution in patients with urinary retention, prostatic hypertrophy or urethral stricture due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take larger amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
This medicine works by changing the way the brain and nervous system respond to pain. It also acts on the part of the brain responsible for coughing.
Legal Status
Classification
Category
Narcotic analgesics, Antitussives
Schedule
Schedule H1
Codeine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 October 2017]. Available from:
[Internet]. 2017 [cited 18 October 2017]. Available from:
[Internet]. 2017 [cited 18 October 2017]. Available from:
DailyMed - Codeine sulfate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 October 2017]. Available from:
Codeine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 October 2017]. Available from:
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Information on this page was last updated on 5 Mar 2020
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.