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Clomifene
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Description
Clomifene is a medicine that has a similar action to the female hormone estrogen. It is used to induce egg production in women who are not able to ovulate due to certain medical conditions.
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Side effects
Major & minor side effects for Clomifene
Flushing
Nausea or Vomiting
Headache
Abnormal vaginal bleeding
Blurred vision
Hot flashes
Difficulty in breathing
Severe stomach ache
Weight gain
Yellowing of skin and eyes
Anxiety and nervousness
Breast pain and tenderness
Trouble sleeping
Uses of Clomifene
What is it prescribed for?
Infertility due to ovulatory failure
This medicine is used for the treatment of infertility caused due to failure of the ovary to release an egg after other reasons for the infertility is ruled out.
Concerns
Commonly asked questions
Onset of action
The effect of this medicine can be observed after 5-10 days of administration.Duration of effect
The effect of this medicine lasts for an average duration of 15-20 days.Safe with alcohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is it habit forming?
No habit forming tendencies were reported.Usage in pregnancy?
Use of this medicine is not recommended for women who are pregnant. Any suspicion of a pregnancy should be ruled out before starting the use of this medicine. It is advised to consult your doctor and discuss the benefits and risks before deciding to take this medicine.Usage while breast-feeding?
Use of this women is not recommended for women who are breastfeeding. If the use of this medicine is absolutely necessary then your doctor may ask to discontinue breastfeeding.
Allergy
This medicine is not recommended for use if you have a known history of allergy to Clomifene or any other component present with it.
Undiagnosed vaginal bleeding
This medicine is not recommended for use if you have abnormal vaginal/uterine bleeding that is yet to be diagnosed.
Thyroid/Adrenal gland disorder
This medicine is not recommended for use in patients having an active disease of the thyroid or adrenal glands.
Endometrial cancer
This medicine is not recommended for use in patients having uterine cancer.
Liver disease
This medicine is not recommended for use in patients having an impairment of liver function.
Warnings for special population
Pregnancy
Use of this medicine is not recommended for women who are pregnant. Any suspicion of a pregnancy should be ruled out before starting the use of this medicine. It is advised to consult your doctor and discuss the benefits and risks before deciding to take this medicine.
Breast-feeding
Use of this women is not recommended for women who are breastfeeding. If the use of this medicine is absolutely necessary then your doctor may ask to discontinue breastfeeding.
General warnings
Evaluation of hormone levels
It is advised to evaluate the levels of sex hormones and rule out diseases like endometrial cancer, ovarian cysts before starting the treatment with this medicine. It is advised to undergo a regular pelvic examination before and during the course of treatment.
Multiple pregnancies
Use of this medicine may increase the risk of multiple pregnancies. it is advised to discuss the risks associated with the use of this medicine.
Visual disturbances
Use of this medicine has been associated with an impairment of vision in some patients. It is advised to not drive vehicles while using this medicine.
Missed Dose
Call the doctor for further instructions if you miss a scheduled dose of this medicine.
Overdose
Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms may include nausea, vomiting, headache, hot flashes etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Danazol
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Clomifene as instructed by the doctor. Your dose is likely to change over the course of treatment. It is advised to undergo tests that will ensure the safe and effective use of this medicine. Follow all the instructions mentioned on the label or the package insert.
Miscelleneous
How it works
This medicine is similar to female sex hormone estrogen and works by stimulating the release of an egg from the ovary.
Legal Status
Classification
Category
Synthetic ovulation stimulants
Schedule
Schedule H
[Internet]. 2017 [cited 5 May 2017]. Available from:
Clomifene - DrugBank [Internet]. Drugbank.ca. 2017 [cited 5 May 2017]. Available from:
Clomiphene | C26H28ClNO - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 5 May 2017]. Available from:
DailyMed - Clomiphene citrate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 5 May 2017]. Available from:
Information on this page was last updated on 16 Nov 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.