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Calmpose 10 MG Injection

Manufactured byRanbaxy Laboratories Ltd.
ContainsDiazepam
CURRENTLY UNAVAILABLE

Description

Calmpose 10 MG Injection is an anticonvulsant medicine, which is used to relieve the symptoms of seizures, anxiety, muscle spasm, and alcohol withdrawal. It is also used for sedation in surgical procedures.
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Substitutes

List of substitutes for Calmpose 10 MG Injection

Dizep 10 MG Injection
Intas Pharmaceuticals Ltd.
Starlium 10 MG Injection
Cadila Pharmaceuticals Ltd.
Zepose 10 MG Injection
Cipla Ltd.

Side effects

Major & minor side effects for Calmpose 10 MG Injection

Constipation

Nausea or vomiting

Dizziness

Sense of imbalance

Headache

Sleepiness

Indigestion

Irregular heartbeat

Shortness of breath

Itching or rash

Unsteady walk

Decrease in frequency of urination

Skin rash

Irritability

Loss of appetite

Diarrhea

Uses of Calmpose 10 MG Injection

What is it prescribed for?

Anxiety

This medicine is used in the treatment of anxiety disorders. Uneasiness, difficulty in sleeping, sweating of hands and feet are some of the symptoms of anxiety disorder.

Alcohol withdrawal

This medicine is used in the treatment of symptoms of alcohol withdrawal like hallucinations, anxiety, and seizures.

Muscle spasm

This medicine is used to relieve skeletal muscle spasm which occurs due to an inflammation of the muscle or joints.

Adjunct prior to endoscopic procedures

This medicine is used in to relieve the symptoms of anxiety or stress in the patients undergoing endoscopic procedures.

Preoperative sedation

This medicine is used to relieve the symptoms of anxiety and tension in patients undergoing surgical procedures.

Status Epilepticus

This medicine is used in the acute management of status Epileptieus, a severe type of seizure which lasts longer than 5 minutes, and the patient experience consecutive seizure episodes even before recovering from the previous episode.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time required for this medicine to show its action is not clinically established.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    Habit-forming tendencies were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to diazepam, or any other inactive ingredients present in the formulation.

Myasthenia gravis

This medicine is not recommended for use in patients with myasthenia gravis due to the increased risk of serious adverse effects.

Narrow-angle glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma since it may worsen the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

General warnings

Suicidal thoughts

This medicine may cause suicidal behavior in some patients. This risk is especially higher on the prolonged usage of the medicine. Patients should be monitored closely for any changes in behavior and mood; any such changes should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of severe adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Drug dependence

This medicine has the potential to cause drug dependence and abuse. This risk is especially higher if the medicine is used for a prolonged period of time. Patients should be monitored closely for any change in mood and behavior during treatment with this medicine. Abrupt discontinuation is not recommended since it may cause withdrawal symptoms. Withdrawal of therapy should be done gradually with close monitoring.

Concomitant use of opioids

Coadministration of diazepam and opioids like morphine, codeine, tramadol, hydrocodone, or any cough preparations containing these medicines should be avoided since it may increase the risk of sedation, breathlessness, coma, and death. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

Paradoxical reactions

The use of this medicine in psychiatric patients and pediatric patients with hyperactive aggressive disorders may cause paradoxical reactions, including excitability, irritability, aggressive behaviour, agitation, nervousness, hostility, anxiety, sleep disturbances, nightmares, and vivid dreams. Close monitoring for signs of a paradoxical reaction during therapy with this medicine is recommended.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in obese patients

This medicine should be used with caution in obese patients with careful monitoring of symptoms. An increase in dosing intervals might be necessary in some cases. Close monitoring of the patient's condition, while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Cetirizine

Metoclopramide

Opioids

Atenolol

Itraconazole

Disease interactions

Closed-angle glaucoma

This medicine is not recommended for use in patients with a known history of closed-angle glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with kidney impairment due to an increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with liver impairment due to an increased risk of worsening of the patient's condition. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Depression

This medicine should be used with caution in patients suffering from depression and other psychiatric disorders due to the increased risk of suicidal thoughts, especially at the beginning of the treatment and at the time of dose change. Patients should be monitored closely for any change in behavior and mood. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works

This medicine works by binding to certain chemicals in the brain and helps in relieving the symptoms.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Benzodiazepines, Benzodiazepine anticonvulsants

Schedule

Schedule H1

[Internet]. Sandoz.ca. 2020 [cited 11 March 2020]. Available from:

https://www.sandoz.ca/sites/www.sandoz.ca/files/Diazepam%20Product%20Monograph.pdf

Diazepam - DrugBank [Internet]. Drugbank.ca. 2020 [cited 11 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB00829

Diazepam [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 11 March 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Diazepam

DailyMed - DIAZEPAM- diazepam injection, solution [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 20 May 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1e6c2f52-73ff-429b-8f1b-9b5b61ce1ac5&audience=consumer

Diazepam Injection BP - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 20 May 2020]. Available from:

https://www.medicines.org.uk/emc/product/6274/smpc

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Information on this page was last updated on 21 May 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.