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Arkamin-H (20 mg/100 mcg) Tablet

Manufactured byUnichem Laboratories Ltd.
ContainsHydrochlorothiazide (20 mg) + Clonidine (100 mcg)
CURRENTLY UNAVAILABLE

Description

Arkamin-H (20 mg/100 mcg) Tablet is a combination medicine used for the treatment of high blood pressure. Frequent monitoring of blood pressure and electrolytes level is necessary during treatment with this medicine.
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Side effectsConcernsUsage

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Substitutes

List of substitutes for Arkamin-H (20 mg/100 mcg) Tablet

Side effects

Major & minor side effects for Arkamin-H (20 mg/100 mcg) Tablet

Mental depression

Anxiety

Dry mouth

Shortness of breath

Constipation

Nausea or Vomiting

Increased urination

Itching or rash

Abdominal and stomach pain

Cramping

Weakness

Uses of Arkamin-H (20 mg/100 mcg) Tablet

What is it prescribed for?

Hypertension

This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of this medicine can be observed within 2 hours of administration of the dose.

  • How long do the effects of this medicine last?

    The amount of time for which this medicine remains active in the body is not clinically established.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    No habit-forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to hydrochlorothiazide, other sulfonamides, clonidine, or any other inactive ingredients present along with these medicines.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Chronic renal failure

This medicine is not recommended for use in patients with a known history of chronic renal failure due to the increased risk of serious adverse effects.

Drug withdrawal

Abrupt discontinuation of this medicine may cause rebound hypertension and side effects such as nervousness, agitation, headache, etc. A gradual dose reduction over 2 to 4 days is recommended to avoid these reactions.

Cerebrovascular disorders

This medicine is not recommended for use in patients with a known history of cerebrovascular disorders due to the increased risk of worsening of the patient's condition.

Depression

This medicine is not recommended for use in patients with a known history of depression due to the increased risk of worsening of the patient's condition.

Use in children

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Hypotension

This medicine may cause a sudden drop in the blood pressure. This risk is especially higher in patients with a history of cardiovascular disorders or electrolyte disturbances. Vital signs should be closely monitored, especially during the first few days of therapy. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Drowsiness

This medicine may cause drowsiness, dizziness, sedation, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Hepatic dysfunction

This medicine should be used with extreme caution in patient's suffering from liver diseases due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Replacement with a suitable alternative may be required based on the clinical condition.

Volume and electrolyte depletion

This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Atenolol

Clomipramine

Insulin

Tizanidine

Antidepressants

Alprazolam

Nonsteroidal anti-inflammatory medicines

Disease interactions

Depression

This medicine is not recommended for use in patients with a known history of depression due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Hypotension

This medicine is not recommended for use in patients with a known history of hypotension due to the increased risk of worsening of the patient's condition.

Renal Dysfunction

This medicine is not recommended for use in patients with a known history of severe renal impairment due to the increased risk of serious adverse effects. For patients with mild to moderate renal impairment, replacement with a suitable alternative may be required based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Hyperuricemia

This medicine should be used with caution in patients with a history of gout or chronic renal failure due to the increased risk of hyperuricemia. Close monitoring of uric acid level is recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. Do not take in larger amounts than prescribed. It is advised to take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Hydrochlorothiazide increases the excretion of water and sodium through the urine. Clonidine relaxes the blood vessels and promotes a smooth flow of blood. Their combination is thus effective in reducing the blood pressure.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antihypertensive combinations, Antiadrenergic agents (central) with thiazides

Schedule

Schedule H

DailyMed - Hydrochlorothiazide tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 28 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7b38ac8a-4540-4eb2-aedd-9aa966d22190

[Internet]. 2017 [cited 28 July 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/040735s004,040770s003lbl.pdf

Clonidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682243.html

EMC [Internet]. 2017 [cited 30 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/283

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Information on this page was last updated on 10 Oct 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.