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Amtas Ht (12.5/5 mg) Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsHydrochlorothiazide (12.5 mg) + Amlodipine (5 mg)
CURRENTLY UNAVAILABLE

Description

Amtas Ht (12.5/5 mg) Tablet is a combination medicine that consists of Amlodipine and Hydrochlorothiazide. It is used for the treatment of hypertension (high blood pressure). Hypertension is a condition in which the force exerted by blood against the blood vessel walls is high, which increases the risk of heart complications such as heart attack and stroke (damage to the brain due to low blood supply). It relaxes the blood vessels by widening them and promotes smooth blood flow. It also increases the excretion of water and sodium, thus resulting in decreased blood pressure. Amtas Ht (12.5/5 mg) Tablet has some common side effects like swelling in your ankles or feet, dizziness, headache, tiredness, stomach upset etc. Consult your doctor if these side effects persist or worsens. Amtas Ht (12.5/5 mg) Tablet can be taken with or without food. The dose and duration of treatment will be determined by your doctor. You should not stop taking Amtas Ht (12.5/5 mg) Tablet without consulting your doctor as it can lead to serious heart conditions. It is also not recommended as initial therapy for high blood pressure. It is best to take this medicine at least 4 hours before going to bed as this medicine increases your frequency of urination. Amtas Ht (12.5/5 mg) Tablet can interact with other medical conditions and medications. Inform your doctor if you have liver, heart and kidney problems, diabetes, or if you are under any medication. To ensure that Amtas Ht (12.5/5 mg) Tablet is working effectively, you should have your blood pressure, kidney function, electrolyte levels, and blood sugar levels tested regularly. Amtas Ht (12.5/5 mg) Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Substitutes

List of substitutes for Amtas Ht (12.5/5 mg) Tablet

Side effects

Major & minor side effects for Amtas Ht (12.5/5 mg) Tablet

Increased urination

Itching or rash

Abdominal and stomach pain

Dry mouth

Joint pain, stiffness, and swelling

Cramping

Weakness

Difficulty in breathing

Dizziness

Increased heartbeat

Redness of face, neck, arms and chest

Heartburn

Acid or sour stomach

Anxiety

Diarrhea

Constipation

Sweating

Uses of Amtas Ht (12.5/5 mg) Tablet

What is it prescribed for?

Hypertension

Hypertension refers to an abnormal increase in blood pressure which may lead to other heart conditions over time. Amtas Ht (12.5/5 mg) Tablet is used in the treatment of high blood pressure which may be caused by genetic or environmental factors. It relaxes the blood vessels by widening them. It also flushes out excess salt from your body. Combining both these effects, Amtas Ht (12.5/5 mg) Tablet is highly effective in treating hypertension.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Amtas Ht (12.5/5 mg) Tablet can be seen within 2 hours after taking it.

  • How long do the effects of this medicine last?

    The effect of Amtas Ht (12.5/5 mg) Tablet lasts for an average duration of 24 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Avoid alcohol consumption when taking this medicine. Amtas Ht (12.5/5 mg) Tablet and alcohol together have a higher blood pressure-lowering effect, and symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate may occur.

  • Is this a habit forming medicine?

    No habit forming tendency has been reported for Amtas Ht (12.5/5 mg) Tablet.

  • Can this medicine be taken during pregnancy?

    Amtas Ht (12.5/5 mg) Tablet is not recommended during pregnancy as it may lead to various complications in your foetus. Consult your doctor if you are pregnant or planning a pregnancy. Your doctor may advise a safer alternative based on your clinical condition.

  • Can this medicine be taken while breast-feeding?

    Amtas Ht (12.5/5 mg) Tablet is not recommended while breastfeeding. Your doctor may prescribe the medicine if the benefits are greater than the risk or switch to an alternative medicine based on your condition.

Allergy

Amtas Ht (12.5/5 mg) Tablet is not recommended if you have a known allergy to any of the ingredients present in this medicine. Seek medical attention in case of symptoms such as skin rashes, hives (itchy, painful eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Anuria

Anuria is a condition where the kidney is unable to produce urine. Amtas Ht (12.5/5 mg) Tablet can lead to a loss of electrolytes like sodium and potassium, magnesium ions, etc. from your body which may lead to further kidney damage.

Warnings for special population

Pregnancy

Amtas Ht (12.5/5 mg) Tablet is not recommended during pregnancy as it may lead to various complications in your foetus. Consult your doctor if you are pregnant or planning a pregnancy. Your doctor may advise a safer alternative based on your clinical condition.

Breast-feeding

Amtas Ht (12.5/5 mg) Tablet is not recommended while breastfeeding. Your doctor may prescribe the medicine if the benefits are greater than the risk or switch to an alternative medicine based on your condition.

General warnings

Liver disease

Use Amtas Ht (12.5/5 mg) Tablet with extreme caution if you have liver problems or obstruction in the bile duct. This medicine is largely excreted in bile (fluid secreted by the liver for digestion). This can increase the risk of side effects on your liver due to a higher level of medicine in the blood. Consult your doctor for a dose adjustment or alternate medicine.

Volume and electrolyte depletion

Amtas Ht (12.5/5 mg) Tablet may alter the blood volume and electrolyte levels in some cases causing dizziness, dry mouth etc. This risk is especially higher if you have kidney and liver problems. Consult your doctor if you have any severe symptoms.

Kidney diseases

Amtas Ht (12.5/5 mg) Tablet may cause azotemia (increase in the level of blood urea and nitrogen) if you have severe kidney problems. While taking this medication, it is important to monitor your kidney function. Based on the clinical situation, your doctor may consider appropriate dosage adjustments or replacements with a suitable alternative.

Use in children

Amtas Ht (12.5/5 mg) Tablet is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically known.

Driving and operating machines

Some individuals may experience dizziness or sleepiness as a result of Amtas Ht (12.5/5 mg) Tablet. If you have any of these symptoms while taking this medication, you should avoid performing tasks that need high mental attention, such as driving or operating machines.

Missed Dose

If you forget to take a dose of Amtas Ht (12.5/5 mg) Tablet, take it as soon as you remember. If it is time for the next dose, skip the missed dose and take your next dose at your usual time. Do not double up your dose.

Overdose

Never take more than the prescribed dose. Seek immediate medical attention if you have taken an overdose of Amtas Ht (12.5/5 mg) Tablet. In case of an overdose, symptoms like drowsiness, nausea and vomiting can be seen.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Avoid alcohol consumption when taking this medicine. Amtas Ht (12.5/5 mg) Tablet and alcohol together have a higher blood pressure-lowering effect, and symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate may occur.

Interaction with Medicine

Dexamethasone

Itraconazole

Rifampicin

Insulin

Antidepressants

Nonsteroidal anti-inflammatory medicines

Carbamazepine

Pregabalin

Disease interactions

Diabetes

Amtas Ht (12.5/5 mg) Tablet should be used with caution if you have Diabetes mellitus due to the increased risk of altered blood sugar levels. Monitor your blood sugar levels regularly while taking this medicine.

Hyperuricemia

Amtas Ht (12.5/5 mg) Tablet should be used with caution if you have a history of kidney failure, due to the increased risk of hyperuricaemia (high blood uric acid level). Your doctor will suggest tests to closely monitor your blood uric acid levels.

Cardiogenic shock

Amtas Ht (12.5/5 mg) Tablet may cause a decrease in blood pressure. The risk is high if you have conditions such as volume depletion (excess loss of salt and fluid in the body due to excessive vomiting, diarrhoea, burns, kidney problems, etc.) or if you are treated with high-dose diuretics (medications that increases the removal of water and salt from the body via urine).

Hypotension

Amtas Ht (12.5/5 mg) Tablet may cause a decrease in blood pressure. The risk of serious complications is high if you have conditions such as volume depletion (excess loss of salt and fluid in the body due to excessive vomiting, diarrhoea, burns, kidney problems, etc.) or if you are treated with high-dose diuretics (medications that increases the removal of water and salt from the body via urine).

Hyperlipidaemia

Hyperlipidaemia is a condition in which there is an increase in the level of fat or lipids in the blood. Amtas Ht (12.5/5 mg) Tablet should be used with caution as it can increase your cholesterol levels and may worsen your condition.

Food interactions

Consumption of grapefruit juice is not recommended during treatment with Amtas Ht (12.5/5 mg) Tablet. Grapefruit juice can increase the absorption of this medicine in your blood. This could lead to excessive lowering of blood pressure or worsen the side effects.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Amtas Ht (12.5/5 mg) Tablet with or without food. Avoid taking the medicine in larger amounts than prescribed. If you experience any side effects after using this medicine, contact your doctor on priority. Do not stop using this medication without consulting your doctor as it may cause serious heart conditions. Take it in the daytime to avoid getting up in the middle of the night to urinate. Your doctor may suggest blood pressure and kidney function tests to ensure it is working effectively and safely. Maintaining a strict diet and exercise regimen while taking Amtas Ht (12.5/5 mg) Tablet will help you get the maximum benefits out of your treatment.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Amtas Ht (12.5/5 mg) Tablet contains Hydrochlorothiazide and Amlodipine. It is a combination medicine used in lowering high blood pressure when single medicine is not effective. Hydrochlorothiazide increases the excretion of water and sodium through urine. Amlodipine relaxes the heart muscles and the blood vessels.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Thiazide diuretics, Calcium channel blocking agents, Antihypertensive combinations

Schedule

Schedule H

Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 13 September 2021].

https://medlineplus.gov/druginfo/meds/a692044.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMLODIPINE- amlodipine besylate tablet. [online] Available at: < [Accessed 13 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b>

Dailymed.nlm.nih.gov. 2021. DailyMed - hydrochlorothiazide- Hydrochlorothiazide tablet. [online] Available at: < [Accessed 14 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7b38ac8a-4540-4eb2-aedd-9aa966d22190>

Medicines.org.uk. 2021. Amlodipine 10 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 13 September 2021].

https://www.medicines.org.uk/emc/medicine/24889>

Medicines.org.uk. 2021. Amlodipine 5 mg Tablet - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 13 September 2021].

https://www.medicines.org.uk/emc/product/2125>

Pubchem.ncbi.nlm.nih.gov. 2021. Amlodipine. [online] Available at: < [Accessed 13 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/2162>

Pubchem.ncbi.nlm.nih.gov. 2021. Hydrochlorothiazide. [online] Available at: < [Accessed 15 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3639>

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Information on this page was last updated on 16 Sep 2021

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