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AFF Tablet
Manufactured byQ-CHECK PHARMACEUTICALS
ContainsAtorvastatin (10 mg) + Fenofibrate (160 mg) + Folic Acid (5 mg)
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Description
AFF Tablet is a combination medicine which may be used for the treatment of combined hyperlipidemia in patients with normal kidney and liver function. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.
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Substitutes
List of substitutes for AFF Tablet
Side effects
Major & minor side effects for AFF Tablet
Difficulty in breathing
Chills and fever
Itching and skin rash
Nausea and vomiting
Headache
Shortness of breath
Weakness
Stuffy nose
Increased sensitivity of the skin to sunlight
Cough
Difficulty in swallowing
Diarrhea
Joint pain
Muscle pain
Difficulty in falling or staying asleep
Fever
Uses of AFF Tablet
What is it prescribed for?
Combined hyperlipidemia
This medicine may be used to treat combined hyperlipidemia, a condition characterized by an increased amount of bad cholesterol (LDL) and triglycerides and a decreased amount of good cholesterol (HDL) in the blood.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The anti-hypercholesteremic effect of this medicine is cumulative and may take up to 3 to 5 days to show its results.How long do the effects of this medicine last?
The time until this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, headache, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.Is this a habit forming medicine?
No habit forming tendency has been reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to fenofibrate, atorvastatin, folic acid, or any other inactive ingredients present along with the formulation.
Renal dysfunction
This medicine is not recommended for use in patients with kidney diseases due to the increased risk of severe adverse effects.
Gallbladder disease
This medicine is not recommended for use in patients with a known history of gallbladder diseases due to the increased risk of gallbladder stones.
Liver disease
This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of severe adverse effects.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Altered blood sugar levels
This medicine may cause an alteration in the blood sugar levels. This risk is especially higher in patients with diabetes mellitus. Close monitoring of blood sugar levels may be necessary based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Muscle degradation and Rhabdomyolysis
This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This may cause symptoms such as severe tiredness and weakness. This risk is especially higher in the elderly population and in patients with active muscle disorders. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Alcohol consumption
This medicine may cause liver and kidney injuries in patients consuming alcohol very frequently and in large quantities. Hence, the consumption of alcohol should be avoided during treatment with this medicine.
Use in pediatrics
This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.
Stroke
This medicine is not recommended for use in patients recovering from a stroke since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.
Cholelithiasis
This medicine should be used with caution due to the increased risk of gallbladder stones. This risk is especially higher in patients with a history of liver or gallbladder diseases. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Increase in serum creatinine levels
Close monitoring of kidney function is recommended in patients receiving this medicine due to the increased risk of elevated serum creatinine levels. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Concomitant Oral Anticoagulants
This medicine should be used with caution in patients receiving anticoagulants due to the increased risk of excessive bleeding. Close monitoring of prothrombin time and INR, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Cognitive impairment
This medicine may cause forgetfulness, memory loss, confusion, etc. in some patients. These side effects are reversible and usually disappear once the medicine is discontinued.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, headache, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Atazanavir
Hypoglycemic agents
Azithromycin
Erythromycin
Cyclosporine
Disease interactions
Cognitive Impairment
This medicine should be used with caution in patients with cognitive impairment due to the increased risk of worsening of the patient's condition. Close monitoring of the patient for any changes in mood or behavior is recommended. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Diabetes
This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Rhabdomyolysis
This medicine is not recommended for use in patients with a known history of rhabdomyolysis due to the increased risk of kidney failure and death. Any symptoms such as muscle pain, weakness, or joint pain and swelling should be reported to the doctor on priority. Replacement with a suitable alternative should be considered under your doctor's supervision.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of adverse effects such as dizziness, muscle pain, fever and chills, headache, swelling of hands and feet, vomiting, skin rash, etc.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Atorvastatin reduces the level of cholesterol in the blood. Fenofibrate increases the natural lipid breakdown process with the help of the enzyme lipoprotein lipase. This removes the bad cholesterol (LDL) and triglycerides from the blood and increases the levels of good cholesterol (HDL). Folic acid is essential for the production of certain vital components that are necessary for the maintenance of normal body functions.
Legal Status
Classification
Category
Statins, Fibric acid derivatives, Antihyperlipidemic combinations, Vitamins
Schedule
Schedule H
[Internet]. Medlineplus.gov. 2019 [cited 13 May 2019]. Available from:
[Internet]. Medlineplus.gov. 2019 [cited 13 May 2019]. Available from:
[Internet]. Dailymed.nlm.nih.gov. 2019 [cited 13 May 2019]. Available from:
[Internet]. Drugbank.ca. 2019 [cited 13 May 2019]. Available from:
Atorvastatin | C33H35FN2O5 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 23 February 2017]. Available from:
Related Questions
Information on this page was last updated on 3 Jul 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.