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Advan THF Cream

Manufactured byALEMBIC LTD
ContainsTretinoin (0.025 %w/w) + Hydroquinone (2 %w/w) + Fluocinolone (0.01 %w/w)
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Description

Advan THF Cream is a combination medicine that consists of Tretinoin, Hydroquinone and Fluocinolone which is used for the short-term treatment of melasma in adults. Melasma is a condition where dark spots appear on your cheeks and forehead that is caused by hormonal changes generally during menopause or pregnancy. Advan THF Cream may cause some side effects like rashes, blistering of the skin, irritation or burning sensation at the application site. Consult your doctor if these side effects persist or worsen. Before beginning the treatment, your doctor may perform a patch test to check if this medicine is safe and non-allergenic for you. It is done as this medicine may cause severe allergic reactions on the skin and asthma attacks in some cases. Advan THF Cream is for external use only. Clean and dry the affected area. Apply a thin layer over the affected parts of the skin. Avoid contact with your eyes, nose and mouth. Rinse with water immediately if the medicine comes in contact with these areas. Advan THF Cream should be used 30 minutes before bedtime for better results. It may take a few days or weeks for improving your condition. Therefore, it is advised to complete the whole treatment with this medicine as prescribed. Advan THF Cream should be used only after consultation with your doctor if you are pregnant or are breastfeeding. Inform your doctor if the condition has not cleared up after four weeks of treatment.

Substitutes

List of substitutes for Advan THF Cream

Side effects

Major & minor side effects for Advan THF Cream

Burning or stinging sensation at application site

Itchy and dry skin

Peeling and blistering of skin

Skin rash

Uses of Advan THF Cream

What is it prescribed for?

Melasma

Advan THF Cream is used to treat moderate-to-severe melasma, a skin condition in which grey-brown patches appear on your face that is usually caused due to hormonal changes during pregnancy.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The amount of time taken for Advan THF Cream to show its effect is not known.
  • How long do the effects of this medicine last?

    The amount of time for which Advan THF Cream remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?

    No habit-forming tendencies were reported for Advan THF Cream.
  • Can this medicine be taken during pregnancy?

    Advan THF Cream is not recommended to be used in pregnancy unless prescribed by your doctor. Consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?

    Advan THF Cream is not recommended to be used during breastfeeding unless prescribed by your doctor. Consult your doctor before using this medicine.

Allergy

Advan THF Cream is not recommended for use if you are allergic to Tretinoin, Isotretinoin, Retinoids, Hydroquinone, Fluocinolone or any other ingredients present along with this formulation. In some cases, it may cause serious allergic reactions like an episode of asthma. If you notice any symptoms such as a skin rash, itching/swelling on the skin, breathing difficulty, etc., seek medical attention immediately.

Warnings for special population

Pregnancy

Advan THF Cream is not recommended to be used in pregnancy unless prescribed by your doctor. Consult your doctor before using this medicine.

Breast-feeding

Advan THF Cream is not recommended to be used during breastfeeding unless prescribed by your doctor. Consult your doctor before using this medicine.

General warnings

Skin sensitivity test

It is advised to take a sensitivity test or patch test to rule out the possibility of an allergic reaction before starting the regular use of Advan THF Cream.

Sun exposure

Use of Advan THF Cream may cause severe undesirable effects to the skin on sun exposure. You are advised to take appropriate precautionary measures like sunscreen while stepping out into sunlight during treatment with this medicine.

Other skin creams

Advan THF Cream may interact with other skincare or medicinal products. Consult your doctor before starting the use of other skincare medicines along with this cream.

Cutaneous reactions

Advan THF Cream may cause local skin irritation such as mild burning sensation, itching, dryness, peeling, and blistering of the skin, etc. Contact your doctor if the symptoms do not subside or become severe.

Missed Dose

Apply the missed dose of Advan THF Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Advan THF Cream is not likely to cause any serious side effects. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Benzoyl Peroxide (Topical)

Salicylic Acid

Methoxsalen

Disease interactions

Infections

Advan THF Cream should be used with extreme caution if you have any infection as this medicine can suppress the immune system and may worsen your condition. Consult your doctor before using this cream if you have any infection.

Hypoadrenocorticism

Advan THF Cream should be used with extreme caution if you have hyperadrenocorticism which is a condition where the adrenal glands secrete an excess of steroidal hormones in the body. Consult your doctor before using this cream if you have this condition.

Sunburn

Advan THF Cream is not recommended for use in case of sunburn due to the increased risk of worsening your condition. Your doctor may advise an alternative medicine based on your condition.

Eczema

Advan THF Cream is not recommended for use if you have eczema due to the increased risk of severe irritation to the eczematous skin. Your doctor may advise an alternative medicine based on your condition.

Food interactions

Information not available.

Lab interactions

Information not available.
Apply a thin layer of Advan THF Cream to the affected area once a day. Use it at least 30 minutes before bedtime or as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor. Keep away from the reach of children and pets. Ensure that unused medicine is disposed of properly.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

Tretinoin works by promoting the repair, growth and maturation of skin cells. Hydroquinone reduces the formation of pigments that causes darkening of the skin. Fluocinolone inhibits the release of certain chemical substances that causes inflammation or swelling. Together they can counteract the symptoms of melasma.

Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Topical depigmenting agents

Schedule

Schedule H

Drugs, H., 2021. Tretinoin Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 16 September 2021].

https://medlineplus.gov/druginfo/meds/a682437.html>

Drugs, H., 2021. Fluocinolone Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 16 September 2021].

https://medlineplus.gov/druginfo/meds/a682271.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - TRI-LUMA- fluocinolone acetonide, hydroquinone, and tretinoin cream. [online] Available at: < [Accessed 16 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a35fa709-5eb5-4429-b38f-f1e0019bf0ee>

Dailymed.nlm.nih.gov. 2021. DailyMed - TRETINOIN CREAM- tretinoin cream. [online] Available at: < [Accessed 16 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=745cc3ce-60b4-4479-a055-316817567949>

Dailymed.nlm.nih.gov. 2021. DailyMed - ACTIVE 4- hydroquinone cream. [online] Available at: < [Accessed 16 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd90482e-c89f-429d-b861-f1220ec804d1>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 16 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021112s006lbl.pdf>

Related Questions

Question:
Advan cream is safe or not can Advan cream whiten the skin and how many days take to see   results.....more
Answer from Dr. Prof. C.R.V.Narasimhalu
It depends on the grade of pigment skin.. for detailed information do direct onl...more
Question:
How is advan cream for skin lightening ...??? Or some other better for lightening............???????
Answer from Dr. Prem Kishore Srivastava
Advan cream is Skin lightening Cream but it's use depend on type of skin so you ...more
Question:
Is advan face cream changes skin complexion? Is there any side effects? Please suggest me best medic...more
Answer from Dr. Shaurya Rohatgi
There can be several causes why your skin would turn dark or you may get pigment...more
Question:
Is advan cream safe to use?? I have acne scars and somebody advised me to use it. I am a breastfeedi...more
Answer from Dr. Anusha Katare
This cream wont help you with scars.
Question:
Good morning doctors. I have been suggested to use redefining radiance advan cream by my doctor but ...more
Answer from Dr. Anusha Katare
Hi. It doesn't contain steroid. Advan THF cream contains steroid.
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Information on this page was last updated on 22 Nov 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.