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Description
Actinocin Injection is an antineoplastic agent which is used to treat various types of cancers that affect the uterus, testicles, Kidneys, soft tissues, skeletal muscles and bones. This medicine is also used in the treatment for solid tumours. It should be used only under the supervision of a qualified physician. Close monitoring of liver function and kidney function are necessary while receiving this medication.
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Substitutes
List of substitutes for Actinocin Injection
Side effects
Major & minor side effects for Actinocin Injection
Diarrhea
Heartburn
Blood in the urine or stools
Mouth sores
Joint pain
Skin Rash
Vomiting
Uses of Actinocin Injection
What is it prescribed for?
Wilm's Tumour
This medicine is used in the treatment of Wilm's Tumour (a malignant tumor which occurs in the kidney).
Ewing's Sarcoma
This medicine is used in the treatment of Ewing's sarcoma, a type of cancer which affects the bone or soft tissues surrounding the bone such as nerves or cartilage.
Rhabdomyosarcoma
This medicine is used in the treatment of Rhabdomyosarcoma, a type of cancer that affects the skeletal muscle cells (rhabdomyloblasts).
Testicular Cancer
This medicine is used in the treatment of Testicular Cancer, a type of cancer that affects the testicles where the male hormones and sperms are secreted
Trophoblastic Disease
This medicine is used in the treatment of Trophoblastic Disease, a rare type of cancer in which trophoblast cells grow abnormally in the uterus after conception.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
The amount of time required for this medicine to show its action is not clinically established.How long do the effects of this medicine last?
The amount of time for which this medicine remains active in the body is not clinically established.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
No habit-forming tendencies were reported.Can this medicine be taken during pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.Can this medicine be taken while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Allergy
This medicine is not recommended for use in patients with a known allergy to Dactinomycin, or any other inactive ingredients present in the formulation.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings
Extravasation
This medicine should be administered only under the supervision of qualified healthcare professionals. if extravasation occurs, interrupt the infusion or injection as soon as possible and apply ice.
Infections
Use of this medicine may affect the immune system, making you susceptible to opportunistic infections from a wide variety of pathogens. Use of this medicine is not recommended if you have an active infection. If a serious infection develops, consult your doctor immediately and discontinue the use of this medicine based on the doctor's advice.
Liver Disease
This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Kidney Disease
This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Bone marrow suppression
This medicine should be used with caution since it may increase the risk of myelosuppression (decreased bone marrow function). Regular monitoring of blood cells count is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Adalimumab
Influenza vaccine H1N1 live
Clozapine
Mumps virus Vaccine
Certolizumab
Polio virus vaccine Live,Trivalent
Disease interactions
Infections
This medicine should be used with extreme caution in patients with a history of recurrent infections due to the increased risk of myelosuppression. Initiation of therapy with this medicine in patients with active infections is not recommended. Patients susceptible to infections should be monitored closely during treatment with this medicine. An alternative treatment option may be necessary in some cases based on the clinical condition.
Kidney Disease
This medicine should be used with caution in patients with kidney disease due to the increased risk of severe adverse effects. Regular monitoring of kidney function, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Liver Disease
This medicine should be used with caution in patients with liver disease due to the increased risk of severe adverse effects. Regular monitoring of liver function, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous
How it works
It works by inhibiting and slowing the growth of the cancer cells in the body.
Legal Status
Classification
Category
Antibiotics/antineoplastics
Schedule
Schedule H
DailyMed - DACTINOMYCIN- dactinomycin injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 7 December 2018]. Available from:
[Internet]. Accessdata.fda.gov. 2018 [cited 7 December 2018]. Available from:
Dactinomycin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 December 2018]. Available from:
COSMEGEN LYOVAC - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 7 December 2018]. Available from:
Related Questions
Information on this page was last updated on 29 Aug 2019
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.