Hi, there is no thing called permanent cure, as long as we live in this toxic environment, we are prone to have these conditions and all we can do is, keep preventing the conditions by fixing the underlying problems.
Now, to help your wife we will need to repair her gut, feed good bacteria and yeast in the form of probiotics foods. Avoid all the antigenic and inflammatory foods. Fill in nutrient deficiencies. Detox her system.
For doing all this i would need more details
Next Steps
let me know if further help required