Hello, I’ve been sufferring from reccurent mouth ulcers for over 5 years. It started when I was 23 years old. Without prednisone, I always have at least 5 mouth ulcers. I have never had zero ulcers these past 5 years. I feel weak and tired when they increase to 20-30 ulcers. I tried anti-virals and they didn’t get any better. I’ve been on colchicine for 4 days, but they are getting worse, not better. My igm is always high. In the 400 range. Blood tests show I also have chronic inflammation.