Hello, I understand your concern. Let me clarify a few things:
Fibromyalgia is a common cause of chronic widespread pain when scans and blood tests are normal. That is why your doctor has started you on duloxetine, which is a standard treatment.
Allergy test results show sensitization (your immune system reacts strongly), but this usually causes allergic symptoms such as sneezing, runny nose, asthma, or skin rashes—not chronic muscular pain.
Mast Cell Activation Syndrome (MCAS) is rare and typically presents with repeated episodes of allergy-like symptoms (flushing, swelling, low blood pressure, abdominal pain, rashes), not just chronic muscle pain.
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Based on your description, allergies or MCAS are very unlikely to explain your muscle pain. Fibromyalgia remains the most likely diagnosis, and your doctor’s treatment approach is correct.
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That said, if you develop symptoms like repeated hives, flushing, swelling, or severe allergic reactions, then further evaluation for mast cell–related disorders may be needed.