Suffered from intrusive thoughts and depression for 8 years approx. Intitial 3_4 years without treatment and last 4 years on treatment with multiple antidepressants(escitalopram/sertrailne/Mirtazapine).. dose escalation was tried... Combination was also tried to no avail. I felt antidepressants aren't working infact making me feel worse and causing me feel agigated, unease and a very different feeling like increasing my energy level, mind racing(taking nap would help). Then I changed my doc and came off my meds and. New meds mere aripiprazole 2mg and vantaxa 5mg. My intrusive thoughts are gone but I feel drowsy and decreased motivation to do anything and can't find pleasure in anything.