8 years before I started treatment for Mixed anxity depression disorder which was caused by excessive consumption of cannabis in depression causing over imagination. . Like, 3 years medicines healed me like a gift in my life. Those were SSRIs only. I was like 1 year more ,I will be healed. . I don't know what happened after that, medicines are not working on me from 5 years. I am switched to new SSRIs everytime ...but like my symptoms are getting worst from these 5 years...I am going back to the condition where I started. I have 100 prescription from 4 or 5 doctor. I am taking oleanz plus in night 1 time from 2 months just to not have heavy head and unstoppable thoughts. And like I am losing hope in my life to get recovered . Can you tell me why my body is no more accepting medicines like SSRIs, bupron and all.