HIGH FEVER WITH PAIN SOLVE WITH DIASES When caused by pathogens (e.g. malaria by Plasmodium ssp.), the term disease is often misleadingly used even in the scientific literature in place of its causal agent, the pathogen. This language habit can cause confusion in the communication of the cause-effect principle in epidemiology, and as such it should be strongly discouraged.[4] In humans, disease is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social