Drug interaction

2025-05-02 17:18:11
My mother has prediabetes. Hba1c stays around 6. Has been prescribed Istamet 50/500 (sitagliptin+metformin) 1 tab before breakfast. Another dr has prescribed Veloz IT 20 (rabeprazole+itopride) before breakfast. Can these two be taken together? Thyronorm 50mcg is prescribed for recently diagnosed TSH of 10. She has bp and liver disease for which she takes carvedilol (betablocker) and rifaximin 550 (antibiotic). She also takes Ecosprin AV 75/20.
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Yes can be taken together

Answered2025-05-07 02:11:34

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Hi, Ideally for someone with prediabetes we don't suggest medicines. Was she already on medicines for diabetes?? She can take all the above mentioned medicines together. That's not an issue Take care

Answered2025-05-06 06:06:18

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First take tab thyroxine after 30 minutes take tab veloz and then istamet just 5 minute before food Fore more detail consult

Answered2025-05-05 16:18:56

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Answered2025-05-05 16:11:24

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Both are different class of drugs . Istamet is for high glucose Veloz if for acidity and vomit . ( to cure side effects related to antihyperglycemics ) No interaction . Shw can take medicine as prescribed .
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Check HBA1C every 2-3 months . Keep check on FBS/PPBS

Answered2025-05-05 15:58:48

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Points to be consider: 1. At Hba1c of 6 - there is no indication of giving medicine ( history seems in complete) 2. Indication for Veloz It 20 prescrintion is not clear 3. Yes these two medicine can be taken bogether, but add vitamin b12 supplementation because both medicine cause vit b12 deficincy if used for long time 4. What is the indication for add rifagut ( liver disease - severity should be speciafic) 5. Why thyronorm is prescribed at TSH of 10 in 70 year old elderly patient- Not need at all
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Required detail past medical history and disease severity assessment and reconsideration of her drug therapy
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Consult on practo for more information

Answered2025-05-05 15:56:09

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Your mother has been prescribed Istamet 50/500 (Sitagliptin + Metformin) for prediabetes (HbA1c ~6), which is an appropriate therapy in early glycemic dysregulation, especially if lifestyle measures alone are insufficient. She has also been advised to take Veloz IT 20 (Rabeprazole + Itopride) before breakfast. This combination is generally used for acid-peptic disorders and delayed gastric emptying. It is safe to be taken along with Istamet, provided she takes them as advised — usually both before breakfast, with a slight gap (e.g., 10–15 minutes apart) to avoid potential minor absorption issues. Important considerations: 1. Thyronorm 50 mcg for newly diagnosed hypothyroidism (TSH 10): This should be taken alone on an empty stomach, at least 30–45 minutes before breakfast or any other medication (including Veloz IT or Istamet). Ideally, she should take Thyronorm early in the morning, then wait 30–45 minutes before taking Veloz IT and Istamet. 2. Carvedilol (beta-blocker): Safe in liver disease and beneficial in portal hypertension if present. No major interaction with other medications listed. 3. Rifaximin 550 mg: Often used in liver disease with minimal systemic absorption. Safe with other listed medications. 4. Ecosprin AV 75/20 (Aspirin + Atorvastatin): Should be taken after dinner, not with the morning medications. Caution is required in liver disease — monitor liver enzymes periodically. Summary of Timing Recommendation: 6:30 AM – Thyronorm 50 mcg with plain water, empty stomach. 7:15 AM – Veloz IT 20 + Istamet 50/500 before breakfast. 8:00 AM – Breakfast. 9:00 AM onwards – Carvedilol, Rifaximin, etc., as per doctor's timing. After Dinner – Ecosprin AV. Final note: Periodic monitoring of liver function tests, TSH, lipid profile, and HbA1c is recommended. Please consult her primary physician for adjustments based on clinical condition.
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mentioned above
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Answered2025-05-05 15:46:43

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Yes you can use. Pl consult.

Answered2025-05-07 03:08:04

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Avoid fried food and spicy food Water intake more Green leafy vegetables and fruits Fiber meal Do connect and consult

Answered2025-05-06 07:19:23

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Kindly consult

Answered2025-05-06 05:11:04

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History not specify about her liver disease ... HbA1c is good so please consult with fasting n post prandialsugar and details of history

Answered2025-05-05 17:07:41

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Continue medication as prescribed by doctor. For prediabetic condition dose is little high. Watch for symptoms of hypoglycemia.

Answered2025-05-05 15:46:01

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