Hello mam/sir history: i have generalized anxiety and moderate depression ,for the same i was prescribed fluoxetine, there was very less improvement in 8 weeks so doctor changed it to bupropion and mirtazapine after 2 months doc tapered off mirtazapine. now i am on bupropion and etizolam. question:i get frightened easily,have become coward. and whenever i go out and socialize i get depressive phase after that. having lack of interest, feeling of guilt, worthless etc, despite being on bupropion for 4 month. why suddenly i have such depressive phase? and what could be possible treatment for anxiety. SSRI SNRI NDRI mirtazapine etizolam, didn't work on anxiety and fear issues.