It would be difficult to analyse your problem without having a look at your dentures, I presume by your statement that since 1 year you are using a denture and find it hard to overcome the perineal problem.
Next Steps
There could be problem with the existing denture and even after repeated corrections you find that it is aggravating your problem of abrasion and boils, then you need to start looking at other treatment options such as implant supported prosthesis.
Health Tips
Implants could be a better solution for you.