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CML(Chronic Myeloid Leukemia),

2026-04-09 13:28:53
My father is suffering from CLM (Chronic Myeloid Leukemia), Local Oncologist advised to take "BOSUTINIB 500 mg" but the Medicine doesn't suits on him, so many health issues arises after taking the Medicine. Earlier he was taking Tab "Imatinib 400" since 2018. Now patellate count has increased,& Hb is very low, Please Guide what to do now
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There are other options which can be tried. But why was imatinib changed? Are there imatinib resistant mutations? Please inform the side effects to your oncologist to consider change of medication

Answered2026-04-11 01:44:47

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Need to know RT-PCR BCR::ABL value. We can change to other 2nd line TKI therapy.
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Do RT PCR BCR::ABL quantitative from good lab. Consultant Hematologist

Answered2026-04-11 04:36:02

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Consultant a medical oncologist/ Hematoncologist for further management and change of medicine.

Answered2026-04-10 12:46:56

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I need to know why imatinib was changed. Inadequate control or resistance. Need to do Imatinib resistance assay based on that we can decide what should be the correct medication

Answered2026-04-10 11:36:39

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