My uncle(60 yrs) having mild fever irregularly and suffered weight loss as well. Has smoking history. AFB report is negative, however chest CT scan says - 1. few enhancing nodular areas of consolidation with speculated margins, some showing central necrosis and adjacent fibrotic pleuroparenchymal bands in basal segments of bilateral lungs. The presence of the lesions is more likely to favour an infectious process like TB, however neoplastic cause cannot be entirely ruled out without biopsy. 2. Few subcentrimetric nodular lesions in the posterior segment of right upper lobe and inferior lingular segments of left upper lobe. 3. Mediastinal lymphadenopathy is something very serious?