Thanks for the query. Dark spots could mean many things. I assume what you mean is probably post acne pigmentation or post inflammatory pigmentation. Targeting through a single agent may not always be fruitful. Meet a qualified Dermatologist to learn more about the diagnosis and treatment options. Combination of different therapeutic agents is always beneficial. Revlite I.e. Q-switched Nd YAG laser has been available for stubborn pigmentation and can be helpful when topical creams fail. You may need multiple sessions. Under experienced hands, lasers are quite safe. Side effects may include laser burns, pigmentation etc. Hope it helps.