My Grandmother was diagnosed with Bed Sore 3 years ago During his 3rd paralysis attack. She is on complete bed rest Her Right side of the body is not in function  due to paralysis.(She didn't  have diabetes or major Blood pressure Problem) The Bedsore at the 4th stage starts Bleed , and it is not Cureing . Every winter it starts Cureing but not fully and during summer time it starts Bleed and during dressing some minute prices of skin is also detached . (During Dressing I used Betadine solution to clean the wound , Betadine ointment and cover the wound with Gauge bandage). Today a very large amount of Blood is released from Bedsore . Kindly Suggest me how I cure it permanently.