My husband is suffering joints pain from last 2.5 year , his pain start after taking some medicine in 2021 acogut ,pan , mucaine gel , Intially his pain start from feet then below knee joints and now both side buttocks and lower back His all test related to spondylopathy is negative HLAB-27 neg and Ra anti ccp ana ena all thing are negative,last year his mri of si joints and pelvis and bone scan of whole body was normal 100% but his pain features is like ankylosing spondylitis, in last 2.6 year his ESR CRP is also normal never increased, i want to know in intial stage can inflammatory markers remains normal or not