Hi there, I am really sorry that you are in so much pain and discomfort. I hope my answer below may help you and ease your suffering. May god bless you.
Ashwani Singh.
AS is a systemic chronic autoimmune spondyloarthropathy which affects large joints and Primarily Spine. It usually affects males more than females(4:1). It seems that you are affected by juvenile form of AS. Only 10% of juveniles with positive HLA - B27 show symptoms of AS. I am assuming that it has been diagnosed in your case as it has a diagnostic criteria, which includes bilateral sacroilitis, -/+ uveitis, HLA- B27 and other orthopaedic and systemic manifestations. It requires multidisciplinary approach.
Treatment includes :
1) physical therapy like cardio respiratory exercises, swimming and others to maintain mobility and flexibility.
2) medical management like pain killers e.g NSAIDs, COX-2 inhibitors. These are first line therapies. Oral steroids are not recommended.
-TNF-alpha-blocking agents- these are second choices and includes infliximab, etanercept, adalimumab and other drugs. Recent clinical studies have shown significant improvement in severity of symptoms with these but they are expensive and have many side effects.
3) Surgical in cases of established deformities or acute fractures or poor lifestyle issues or progressive neurological deficit.
Answered2016-12-13 15:04:54
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