I can understand your concern. Tretiva contains isotretinoin. And yes it has side effects like dryness of skin and mucosa, especially lips. But if you want to reduce your acne on a long term basis, you need to continue isotretinoin. Rarely isotretinoin can affect cholesterol and
liver. Hence regular follow up with investigations is necessary. Your dermatologist is treating you correctly. Follow up with him regularly. For drying of skin and lips you can use emollients and lip balms