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Double marker has very less predictability due to high hormonal level due to multiple pregnancy.need to consult a fetal geneticist for appropriate advice honestly.

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Dual marker tells possibility of Downn’s or Edverd ‘s syndrome which generally have mental retardation Anencephaly in on other hand is with incompatible of living after birth If reports of dual marker in twins gestation are showing increase probability of Down’s syndrome Then one shud do noninvasive maternal blood test for fetal chromosomal sampling or shud confirm with amniocentesis If Dual marker is normal then need not worry n do even quadruple markers for double confirmation Anencephaly can grow for 9 mths n I have seen child servicing for 11 mths post delivery

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