Vaccines should be maintained in the temperature, which was mentioned by the manufacturer. It is not the time that plays a major role. It is the temperature of your vaccine. For example, if the pack says 2 to 8°c and in this 15-minute gap, it goes higher than that then vaccine effect will not be as effective as the vaccine, which is maintained in that particular range. So, without knowing the temperature of your vaccine at the time, the effect can't be predicted
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cold chain is very important for vaccine efficiency.