My mother faces with a problem on her face since last year. It is some thing like holes or collapse on her face. In fact, she has used Botox several times in the last five years. We don't know its a side effect of Botox or Something else. Because its not like regular symptoms of Botox side effect. I have a picture of her problem. I can send it to you, if you want. Moreover, She also suffers from psoriasis.