need to examine and assess properly.... The neck and underarm darkening is commonly seen as a component of Acanthosis Nigricans. Acanthosis nigricans is usually the result of obesity. This is known as obesity-associated acanthosis nigricans. It occurs because obesity can cause insulin resistance (when the body is unable to properly use the hormone insulin), which may lead to high levels of insulin in the blood, affecting the skin cells. Insulin resistance can also cause type 2
diabetes, so acanthosis nigricans can be an early sign that you have diabetes or are at risk of developing the condition. Syndromes and hormone problems Acanthosis nigricans is sometimes associated with an underlying syndrome or hormone problem, such as: Cushing's syndrome â symptoms such as weight gain, bruising and stretch marks caused by very high levels of the hormone cortisol in the body acromegaly â where the body produces too much growth hormone, leading to the excess growth of body tissues over time underactive
thyroid (hypothyroidism) â where your thyroid gland does not produce enough hormones, causing symptoms such as tiredness and weight gain. Acanthosis nigricans is sometimes triggered by medicines, including insulin, corticosteroids, and hormone treatments such as human growth hormone or the contraceptive pill. This is known as drug-induced or medication-associated acanthosis nigricans. In rare cases, acanthosis nigricans can be caused by a faulty gene inherited directly from your parents. This is known as familial or benign genetic acanthosis nigricans. This type is usually passed on in an autosomal dominant pattern, which means it can be passed on if only one of your parents carries the faulty gene. This type of acanthosis nigricans is known as syndromic acanthosis nigricans. you should consult with me online and we can approach the situation accordingly. hope this is helpful.