I am having severe cramps during first day of period and normal bleeding. It doesn't go away with single pain killer of maftal spas also. I Had to go to nearest hospital to get paracetamol 1g injection and then I got the relief. Few months back I was detected with nephrotic syndrome and as a treatment I have taken wysolone which doctor asked me to stop a month back. Right now I am on tacrolimus medicine. Can the period cramps be side effects of these medicines or something else?