It’s not contraindicated by experts. India has not done enough studies but Canadian associations have said it is fine to take the astra Zeneca vaccine even in factor B Leiden patients. The astra Zeneca vaccine described by Canada and Covishield in India are one and the same. So yes, safe to take it in general. I’m assuming she is not on any medication as Factor v generally does not need prophylaxis. But it is better to consult , look at her current status and evaluate. Please take a consult if you need more information.