Hi. The cause of the rashes has to elicited and accordingly the treatment is given. If tge rash was deep seated grain like, then possibility of a condition known as cheiropompholyx exists. Are other sites like soles involved as well? Do you get recurrent allergies or are u allergic to nickel. Does it occur while holding something which is metal-based, any contact with harsh soaps, acids, etc. Systemic non-sedating anti-histamines will help in regards to the itching otherwise. Regards, Dr. Zubin Mandlewala MUMBAI