Hello sir/ Madame, My sister was suffering from depression from January . We waited for 1 and half month to start any medicine . After that doctor recommended for Cilapam Plus. Previous History She had the similar issues earlier as well at the age of 14 and 19 and was diagnosed with Bipolar disorder . Maniac episode also lasted for around more than 6 month. Last year we were feeling that she is having a maniac epsiode but that was bearable .She was excited slightly but that was not harmful for her nor the society. Medicines which she was taking at age of 19 was quitipin and mazetol Problem Now she is taking 5mg of Depran but she has not recovered a bit. she feels lazy with body pain and headache till afternoon but during evenings she is better and continue her daily activities. Doctor recommended to stop Depran and wait for a week and if she still feel unwell , admit her to hospital. Please help what we can do know? Thanks in advance.