It's been one month since I have got extreme skin chaffing, tightening, redness, small blisters and discoloration on my lips and around my lips It started with lips, on my upper lips I noticed small blisters and red and black patches then skin started chaffing and lips got tight. Even a second without moisturizer my lip is getting cut. Then it spread to upper lips and area under the nose Skin is red blistered and lots of chaffing and extremely stiff I took fluconazole tablets once a week for 5 weeks and using moisturex cream on the area But I m seeing no difference.