Firstly, childhood history of breathlessness with diurnal variation (if present) is suggesting bronchial asthma only. If from childhood itself the management hasnt been optimised will cause asthma with fixed airways, thereby showing the current spirometry values here.
It can be difficult to treat asthma category and will have to start on formoterol budesonide MDI 2 puffs daily provided the technique is right.
If your technique is right and you are already on high dose inhalers, you may proceed for an HRCT to rule out other causes of asthma such as ABPA.
Next Steps
MDI formonide 200mcg 2 puffs BD x 3 months
T. acebrophylline 100mg BD x 2 weeks
repeat spirometry after 1 month
Health Tips
avoid all dust, house dust mite