Treatment resistant depression is a known problem. Not giving up is the key, be consistent with treatment, combine medicines with therapy which can be really beneficial. A good trial with medicines, augmentation with some available agents and a proper collaboration with a therapist might help you well.

Hello Friend, Good that you are seeking a help here. For any emotional disturbance, medicine alone can't solve the problem. In parallel, you need to figure out the the root cause for your depression and slowly work on it.. In addition, your physical body illness or discomfort also can add more disturbance to your mind. Chat with me online to discuss in detail, so that a suitable solution that you can follow can be worked out..

Feeling low, having crying spells, sleep and appetite disturbances, and difficulty in concentration and attention are some of the signs of Depression. Consult a Psychiatrist for a detailed assessment. It is likely with medication and counseling the symptoms will improve. If you are feeling suicidal or hopeless consult a Psychiatrist immediately.

Probably, you are in need of other perspectives... You have tried every possible methods which you are equipped with... Seek a professional support... Consult a psychologist...

Are u still getting therapy?