Well, need more details on this query. A T2 hypointense lesion on an MRI brain scan refers to an area in the brain that appears dark on T2-weighted images. This may indicate a variety of conditions, such as a tumor, stroke, or demyelination (loss of the protective covering around nerve cells). However, T2 hypointense lesions can also be benign and not necessarily indicative of a serious condition. For example, small areas of mineralization or iron deposition in the brain can also appear hypointense on T2-weighted images.