Essential Thrombocythemia Kidney Stones

2018-12-21 00:59:43
Hello Team, I am seeking out an expert opinion regarding my sister-in-law’s health condition. She had asthma in past and was allergic to dust. But then in the recent past she was diagnosed with “essential thrombocythemia” wherein her platelet count reaching 14 Lakh mark. In such a condition, a doctor prescribed Imatinib 400 tablet (OD). We were fearing as this is a tablet to fight varieties of cancer. Upon asking as to why this medicine was prescribed, doctor said that he is doubting weather this increase in platelet count is related to myeloproliferative neoplasms cancer or acute leukaemia, so he prescribed this medication. Now last week she was diagnosed with stones in both kidney and we are suspecting this medicine to be the cause of that. She is getting married in April and we have no clue where to go and whom to ask for help. I am sharing all the recent reports. Kindly guide us in right direction. Do we really need to take this medication ? Is she developing cancer ?
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Answers (2)

Please meet a medical oncologist or hematologist in person with all available reports...

Answered2018-12-30 13:44:45

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Imatinib is recommended for bcl-abl positive chronic myeloid leukemia(CML) and not for essential thrombocythemia. Usually in essential thrombocythemia hydroxyurea or interferon are drug of choice. But any patient with high platelet count  CML to be ruled out.you did not attach the reports.as per my knowledge imatinib will not produce renal stone it might be incidental finding. So rediscuss with your doctor or meet good clinical hematologist in nearby place. Plz attach bcr able report

Answered2018-12-21 04:37:31

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