Hello,
Methacholine challenge test is a provocative test ( which means administration of methacholine will lead to development of chest tightness/ wheezing/ breathlessness/ cough).
Sometimes this test itself leads to worsening in the clinical condition. So I would advise you to consider for consulting a Pulmonologist regarding your problems as there are other helpful tests for establishing a diagnosis of asthma
Next Steps
Please consult a specialist (pulmonologist) for addressing these issues
Health Tips
Avoid cold food/ drinks, Strictly avoid smoke and wear masks/ protective gear for avoiding exposure to pollution