Hello dear Practo user, can you please describe your problem in detail. You mentioned just depression, is it first time in your life or previously also you have been suffering from some psychological problem. It's only 10 days so you have to wait for complete response of medicine.

This medicine has combination of two ingredients, one olanzapine which usually increases appetite and weight significantly while another fluoxetine which decreased appetite for time being in few patients. As you taking both of these ingredients in this medicine its completely depends on individual's body how that react to these ingredients together. Yes there is a possibility that it can decrease weight but in most of the cases this combination increases weight. I hope you got the answer of your query.