Sepsis crieria is Two of the following 1. Temperature<36 °C (96.8 °F) or >38 °C (100.4 °F) 2.Heart rate>90/min 3Respiratory rate>20/min or PaCO2<32 mmHg (4.3 kPa) 4.WBC<4x109/L (<4000/mm³), >12x109/L (>12,000/mm³), or 10% bands PLUS Suspicious or Confirmed Infection. To answer your question as one-liner....History (complaints)Clinical(Patient full examination), lab (CBC, CRP, Blood or Urine culture)