I had Nissen fundoplication 2 years ago even after having the surgery I had silent reflux. Then I was diagnosed with depression (which was the reason for acid reflux) so I was put mirnite 15 mg and soltus 100mg half tablet. After that I was not having reflux of any sort . 20 days before my dr changed the medication he gave mirnite 15 mg and olimelt 5 mg the initial 15 days I didn't have any symptoms now I am facing symptoms like acid reflux, nausea some times, feeling vomiting when I see the food loss of appetite, will change of medication cause this and why are the symptoms appearing after 15 days. Can symptoms appear after many days is it related to the medication or has the surgery failed I am very worried about it dr pls reply.