Hi there... I understand your concern towards your sisters condition... Treatment options are over the counter pain medications, NSAIDS, steroids,TNF blockers...detailed examination and evaluation is necessary before starting treatment....Ensure that she maintain an appropriate posture while working or sitting or walking....advice her to take frequent stretch breaks and drink lots of water...Discontinue using pillow while sleeping straight... Tell her to avoid lifting heavy objects, especially after bending down,Eat a healthy wholesome meal which should satisfy your minerals and proteins requirement...be in a regular fallow up with your rheumatologist they will do the needful.