TSH > 100 suggests you have a overt hypothyroidism. Check for free T4 and anti TPO. Normally hypothyroidism smptoms includes weight gain, hair fall, facial puffiness, cold intolerance, constipation, lack of appetite, dry skin, mental slugishness, menstrual disturbance in females. Untreated hypothyroidism may lead fluid retention , myxedema, pericardial, pleural or ascitic fluid collection may occur. Myxedema coma is most serious form.