Hi. I have been having major mood issues for a few years now. I have extreme irritability and agitation at times - and other times I'm fine. I researched a bit and it looked like I may be low or high in a hormone. Other symptoms I've had include: lack of focus, lack of motivation, fatigue, hot flashes, and waking up at night sweating. The biggest issue is the irritability, which often gets taken out on others.