Hello there,
Well they could be related or could not be.
Your knots mostly are spider veins or vericose if large enough...which causes the entire leg to become heavy.
To be sure about knee you need to get xray of the knee for furthur analysis and advice
Next Steps
If daily activities are not affected,,conservative treatment of medicines and exercise would bring relief to you....if it doesnt help a visit to vascular surgeon is recommended for furthur advice.
regards
Health Tips
Dr Raviraj Francis
MPTh(Rehab),MPT(MSk).UK