Yes, it does cause you some issues with people, when there are some changes in you.
Do you think, whether it is a selective Loneliness, Or,
You have observed, that you are facing this with everyone!!!
Sometimes, some very very trivial incidents would hinder or disrupt our lives like this.
Next Steps
You can choose to handle this, with a professional support.
Consult a psychologist for a better clarity and understanding.