Greetings. Methotrexate is one of the simplest basic oral medication needed for treating psoriasis. However, like with any other medication you'll need to have certain basic baseline testing and monitoring tests while on psoriasis. It does have a few effects like
liver enzyme elevation, blood count reduction but these can be monitored and the duration for which Methotrexate should be taken should be decided by the doctor. If not Methotrexate, discuss other options but each will have it's pro s and cons. Warm regards