Its sad that you are using duphastan to mask your daughters pcos symptoms. Hormones have side effects which are showing up . In recent years, we have a silent and growing epidemic of hormone imbalances amongst women. Why is it a serious problem and why you should not ignore it? Because, If it is not treated early, it can also lead to serious health problems like diabetes, heart disease, and even cancers. Not only the symptoms of hormone imbalance make your life miserable, there is a scientific proof that they also  increase your chances of developing a big disease later on in life, like full-blown diabetes, autoimmune thyroid disease, and even cancers. The BioCycle study (NIH 2009) showed that untreated, hormonal imbalances increase significantly a woman’s  risk to diseases of inflammation – heart disease, diabetes, cancer, and premature aging. It's not normal to have irregular periods  ( early or late), missing periods, spotting between periods, prolonged heavy flow, pains and cramps during cycle, PMS and mood changes before periods, PCOS, Fibroid, Endometriosis,  fertility issues, tiredness, hair fall,  sleep disturbances, weight issues etc. If it is happening to you,  it's a sign of underlying  hormone  imbalance  which needs further evaluation with blood investigations .